Pathogenesis of androgenetic alopecia female and male have similarities but drought bald men theory cannot fully explain the pathogenesis of androgenetic alopecia in women. Female androgenetic alopecia is a Polygenic disease, with or without elevated levels of testosterone. A variety of factors, such as drugs, nutrition, disease, psychological stress can affect female androgenetic alopecia.
Female androgenetic alopecia most circulating Androgen levels in patients with completely normal, may be due to follicular androgen sensitivity of target organs increased or induced by androgen receptors in hair follicles change, or follicular androgen metabolism enzyme defects, due to partial androgen excess. Testosterone levels were significantly higher in patients with small, often accompanied by other symptoms of high Androgen levels, such as women, HIRSUTISM, acne, etc. Women with high blood prolactin is associated with the onset of female androgenic alopecia. In addition, women with androgenetic alopecia forehead hair follicle 5A-reductase levels only half of the men and androgenic activity of the aromatase enzyme and metabolism 2~5 times greater than that of men, so women with forehead hair line intact.
Typical female androgenetic alopecia is the parietal or frontal top of diffuse hair loss, forehead hair line intact. Women tend not to complete hair loss, hair only a reduction of the diameter, shorter hair length, color fades, scalp were visible. Other parts such as genital mutilation, armpits and eyebrows, diffuse shedding may also occur.